Iczer-1 is the series' heroine, a powerful gynoid created by the Cthulhu to be their guardian and future leader. However, when the Cthulhu were taken over by Big Gold, Iczer-1 was jettisoned. She arrived on Earth and somehow got wind of the coming invasion by the Cthulhu, now under Big Gold's command. She was therefore forced to defend the Earth against those she was created to protect.