Alisa is an outspoken, dog-loving Anglophone and multimillionaire heiress. She gets angry at Nanoha halfway through the series for keeping secrets from her friends. Despite this, she cares deeply for her friend. She is a strong-willed person the apparent leader in her small circle of friends. When she has bursts of rage at not fully understanding what's going on, Suzuka is usually there to calm her down. Alisa is proficient with English and loves dogs, owning about ten at her large mansion. Similarly to Nanoha's and Yuuno's first encounter, Alisa found an injuried Arf and took her to be treated in her house under the assumption that the familiar was just a big dog. Nanoha and Yuuno eventually met with Arf at Alisa's home.
In A's, Alisa's role is greatly reduced. Though she takes the lead of helping the new foreign student, Fate, in her integration of Japanese lifestyle, her few on-screen appearances are mostly of her worrying about the fact that Nanoha and Fate are keeping secrets from her and Suzuka. Upon meeting with Arf in her puppy form, Alisa noted that she seemed strangely familiar to her. Alisa and Suzuka are trapped in a magical barrier and bear witness to Nanoha and Fate's battle with Hayate possessed by the Book of Darkness. Later, Alisa, along with the other civilian characters, are let in on the secrets of what Nanoha has been doing all this time.
In the A's epilogue, Alisa still goes to school with Nanoha and Suzuka and remains their close friend.